For more than 30 years, Genentech has been at the forefront of the biotechnology industry, using human genetic
information to develop novel medicines for serious and life-threatening diseases. Today, Genentech is among the
world’s leading biotech companies, with multiple therapies on the market for cancer and other serious medical
conditions. Please take this opportunity to learn about Genentech, where we believe that our employees are our
most important asset.
The following opportunity exists in our South San Francisco, CA, headquarters:
Scientist - Protein Biochemist/Crystallographer
Responsibilities:
The position will play a key role in exploring the structure and functional properties of proteins of therapeutic
interest and their interactions with ligands. He/she will purify, characterize, crystallize and determine the structure
of proteins and protein-ligand complexes, with a focus on developing and implementing automated higher-
throughput methods while contributing to small molecule discovery programs, basic research projects and
participating in multi-disciplinary drug discovery teams. In this position, the candidate will work within a group that
encompasses protein expression, purification, crystallography and NMR spectroscopy. He/she will collaborate with
scientists throughout the Research organization.
Requirements:
A PhD in Structural Biology, Biophysics, Biochemistry or a related discipline is required, in addition to relevant
postdoctoral experience. The candidate will show evidence of sustained productivity and independent
contributions in science, as demonstrated by a strong publication record. He/she should be a technical expert in
protein purification, characterization and crystallization with demonstrated expertise in handling challenging
proteins for structural studies. Strong analytical, organizational and communication skills are essential, as well as
the ability to work independently and in a collaborative team-oriented setting. Experience in solving X-ray crystal
structures of proteins and protein complexes and familiarity with techniques such as ITC, surface plasmon
resonance, ELISAs and/or immunoprecipitation to characterize proteins in support of structural biology is highly
desired.
Genentech is dedicated to fostering an environment that is inclusive and encourages diversity of thought, style,
skills and perspective. To learn more about our current opportunities, please visit: http://careers.gene.com and
reference Req. #1000030878. Please use “Web – PxUniverse” when a source is requested. Genentech is an
equal opportunity employer.